The Safeway Stores Office and Warehouse Building is a historic building near downtown Kansas City, Missouri. The building was designed by Kansas City architects Archer and Gloyd and was built by local contractor J. H. Thompson in 1929. It served as Safeway's regional produce and canned goods warehouse, as well as the regional headquarters for the chain. The warehouse served a region extending from Topeka, Kansas in the west to St. Joseph, Missouri in the north, Columbia, Missouri in the east to Joplin, Missouri in the south.